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Do the Microbiota Influence Vaccines and Protective Immunity to Pathogens?: Issues of Sovereignty, Federalism, and Points-Testing in the Prokaryotic and Eukaryotic Spaces of the Host-Microbial Superorganism

In contrast to live attenuated vaccines, which are designed to induce immunity through a time-limited bloom in systemic tissues, the microbiota is a persistent feature of body surfaces, especially the intestine. The immune responses to the microbiota are idiosyncratic depending on the niche intimacy...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Perspect Biol
Autor principal: Macpherson, Andrew J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793759/
https://ncbi.nlm.nih.gov/pubmed/28432128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a029363
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