Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

BACKGROUND: Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs targeting their parental transcripts of ITCH. However, the role of circ-ITCH in bladder cancer (BCa) was not reported. In the present...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Yang, Chengdi, Yuan, Wenbo, Yang, Xiao, Li, Peng, Wang, Jingzi, Han, Jie, Tao, Jun, Li, Pengchao, Yang, Haiwei, Lv, Qiang, Zhang, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793418/
https://ncbi.nlm.nih.gov/pubmed/29386015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-018-0771-7
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