Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3

Tumor suppressor and upstream master kinase Liver kinase B1 (LKB1) plays a significant role in suppressing cancer growth and metastatic progression. We show that low-LKB1 expression significantly correlates with poor survival outcome in breast cancer. In line with this observation, loss-of-LKB1 rend...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Oncogene
Autors principals: Sengupta, S, Nagalingam, A, Muniraj, N, Bonner, MY, Mistriotis, P, Afthinos, A, Kuppusamy, P, Lanoue, D, Cho, S, Korangath, P, Shriver, M, Begum, A, Merino, VF, Huang, C-Y, Arbiser, JL, Matsui, W, Győrffy, B, Konstantopoulos, K, Sukumar, S, Marignani, PA, Saxena, NK, Sharma, D
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5793218/
https://ncbi.nlm.nih.gov/pubmed/28581518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.164
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars