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Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro

Development of in vitro culture systems for the generation of red blood cells is a goal of scientists globally with the aim of producing clinical grade products for transfusion. Although mature reticulocytes can be efficiently generated by such systems, the numbers produced fall short of that requir...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Trakarnsanga, Kongtana, Wilson, Marieangela C., Heesom, Kate J., Andrienko, Tatyana N., Srisawat, Chatchawan, Frayne, Jan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792592/
https://ncbi.nlm.nih.gov/pubmed/29386568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20491-1
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