Circadian coordination of ATP release in the urothelium via connexin43 hemichannels

Day-night changes in the storage capacity of the urinary bladder are indispensable for sound sleep. Connexin 43 (Cx43), a major gap junction protein, forms hemichannels as a pathway of ATP in other cell types, and the urinary bladder utilizes ATP as a mechanotransduction signals to modulate its capa...

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Udgivet i:Sci Rep
Main Authors: Sengiku, Atsushi, Ueda, Masakatsu, Kono, Jin, Sano, Takeshi, Nishikawa, Nobuyuki, Kunisue, Sumihiro, Tsujihana, Kojiro, Liou, Louis S., Kanematsu, Akihiro, Shimba, Shigeki, Doi, Masao, Okamura, Hitoshi, Ogawa, Osamu, Negoro, Hiromitsu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792455/
https://ncbi.nlm.nih.gov/pubmed/29386573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20379-0
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