Loss of nitric oxide-mediated inhibition of purine neurotransmitter release in the colon in the absence of interstitial cells of Cajal

Regulation of colonic motility depends on the integrity of enteric inhibitory neurotransmission mediated by nitric oxide (NO), purine neurotransmitters, and neuropeptides. Intramuscular interstitial cells of Cajal (ICC-IM) and platelet-derived growth factor receptor-α-positive (PDGFRα(+)) cells are...

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Bibliographic Details
Published in:Am J Physiol Gastrointest Liver Physiol
Main Authors: Durnin, Leonie, Lees, Andrea, Manzoor, Sheerien, Sasse, Kent C., Sanders, Kenton M., Mutafova-Yambolieva, Violeta N.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792210/
https://ncbi.nlm.nih.gov/pubmed/28705804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00045.2017
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