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Detachment-induced E-cadherin expression promotes 3D tumor spheroid formation but inhibits tumor formation and metastasis of lung cancer cells

The epithelial-to-mesenchymal transition is proposed to be a key mechanism responsible for metastasis-related deaths. Similarly, cancer stem cells (CSCs) have been proposed to be a key driver of tumor metastasis. However, the link between the two events and their control mechanisms is unclear. We us...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Powan, Phattrakorn, Luanpitpong, Sudjit, He, Xiaoqing, Rojanasakul, Yon, Chanvorachote, Pithi
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792170/
https://ncbi.nlm.nih.gov/pubmed/28931539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00096.2017
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