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New tricks for an old dog: Brf2-dependent RNA Polymerase III transcription in oxidative stress and cancer

Here, we discuss the role of Brf2, an RNA Polymerase III core transcription factor, as a master switch of the oxidative stress response. We highlight the interplay of Brf2 with the Nrf2/Keap1 pathway, as well as the role of Brf2 in cancer and other possible regulations.

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Publicat a:Transcription
Autors principals: Gouge, Jerome, Vannini, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791813/
https://ncbi.nlm.nih.gov/pubmed/28854119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541264.2017.1335269
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