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Caveolin-1, a driver of invasive phenotype in in-vitro 3D-spheroid assays comprised of high grade GBM cells association with an AKT-inhibited phenotype

INTRODUCTION: Glioblastoma multiforme (GBM) cells display a highly invasive phenotype, a hallmark which counters effective surgical and radiotherapy strategies. Caveolin-1 (Cav-1) is the main structural and functional component of caveolae. The impact of the expression of Cav-1 within a range of tum...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Moriconi, Chiara, Palmieri, Valentina, tornillo, giusy, Fillmore, Helen, Pilkington, Geoffrey J, Gumbleton, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791702/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox238.058
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