Comparative Evaluation of U.S. Brand and Generic Intravenous Sodium Ferric Gluconate Complex in Sucrose Injection: Biodistribution after Intravenous Dosing in Rats

Relative biodistribution of FDA-approved innovator and generic sodium ferric gluconate (SFG) drug products was investigated to identify differences in tissue distribution of iron after intravenous dosing to rats. Three equal cohorts of 42 male Sprague-Dawley rats were created with each cohort receiv...

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Detalhes bibliográficos
Publicado no:Nanomaterials (Basel)
Main Authors: Beekman, Christopher R., Matta, Murali K., Thomas, Christopher D., Mohammad, Adil, Stewart, Sharron, Xu, Lin, Chockalingam, Ashok, Shea, Katherine, Sun, Dajun, Jiang, Wenlei, Patel, Vikram, Rouse, Rodney
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791097/
https://ncbi.nlm.nih.gov/pubmed/29283393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8010010
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