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Reduced Expression of Glutathione S-Transferase α4 Promotes Vascular Neointimal Hyperplasia in CKD

Neointima formation is the leading cause of arteriovenous fistula (AVF) failure. We have shown that CKD accelerates this process by transforming the vascular smooth muscle cells (SMCs) lining the AVF from a contractile to the synthetic phenotype. However, the underlying mechanisms affecting this tra...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Luo, Jinlong, Chen, Guang, Liang, Ming, Xie, Aini, Li, Qingtian, Guo, Qunying, Sharma, Rajendra, Cheng, Jizhong
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791085/
https://ncbi.nlm.nih.gov/pubmed/29127112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017030290
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