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Extracellular Adenosine Stimulates Vacuolar ATPase–Dependent Proton Secretion in Medullary Intercalated Cells

Acidosis is an important complication of AKI and CKD. Renal intercalated cells (ICs) express the proton pumping vacuolar H(+)-ATPase (V-ATPase) and are extensively involved in acid-base homeostasis. H(+) secretion in type A intercalated cells (A-ICs) is regulated by apical vesicle recycling and stim...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Battistone, Maria A., Nair, Anil V., Barton, Claire R., Liberman, Rachel N., Peralta, Maria A., Capen, Diane E., Brown, Dennis, Breton, Sylvie
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5791049/
https://ncbi.nlm.nih.gov/pubmed/29222395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2017060643
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