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Experimental Adaptive Evolution of Simian Immunodeficiency Virus SIVcpz to Pandemic Human Immunodeficiency Virus Type 1 by Using a Humanized Mouse Model

Human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS, originated from simian immunodeficiency virus from chimpanzees (SIVcpz), the precursor of the human virus, approximately 100 years ago. This indicates that HIV-1 has emerged through the cross-species transmission of SIVcpz fro...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Sato, Kei, Misawa, Naoko, Takeuchi, Junko S., Kobayashi, Tomoko, Izumi, Taisuke, Aso, Hirofumi, Nagaoka, Shumpei, Yamamoto, Keisuke, Kimura, Izumi, Konno, Yoriyuki, Nakano, Yusuke, Koyanagi, Yoshio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790958/
https://ncbi.nlm.nih.gov/pubmed/29212937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01905-17
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