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Application of a validated HPLC-PDA method for the determination of melatonin content and its release from poly(lactic acid) nanoparticles

Melatonin is a natural hormone and with the advancement of age its production declines and thereby may result in some neurological disorders. Exogenous administration of melatonin has been suggested as a neuroprotective agent. Due to its low oral bioavailability, the loading of melatonin in polymeri...

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Dades bibliogràfiques
Publicat a:J Pharm Anal
Autors principals: Martins, Leiziani Gnatkowski, khalil, Najeh Maissar, Mainardes, Rubiana Mara
Format: Artigo
Idioma:Inglês
Publicat: Xi'an Jiaotong University 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790749/
https://ncbi.nlm.nih.gov/pubmed/29404064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.05.007
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