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Meta-analysis of three genome-wide association studies identifies two loci that predict survival and treatment outcome in breast cancer

The majority of breast cancers are driven by the female hormone oestrogen via oestrogen receptor (ER) alpha. ER-positive patients are commonly treated with adjuvant endocrine therapy, however, resistance is a common occurrence and aside from ER-status, no unequivocal predictive biomarkers are curren...

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Pubblicato in:Oncotarget
Autori principali: Khan, Sofia, Fagerholm, Rainer, Kadalayil, Latha, Tapper, William, Aittomäki, Kristiina, Liu, Jianjun, Blomqvist, Carl, Eccles, Diana, Nevanlinna, Heli
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790536/
https://ncbi.nlm.nih.gov/pubmed/29423119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22747
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