Germline polymorphism of interferon-lambda3 is clinically associated with progression of renal cell carcinoma

Renal cell carcinoma (RCC) is an immunogenic tumor that shows a metabolic shift to aerobic glycolysis. The immune system can have opposing host-protective and tumor-promoting effects, and aerobic glycolysis suppresses antitumor immunity. In addition to immunostimulatory effect, increasing numbers of...

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Pubblicato in:Oncotarget
Autori principali: Nukui, Akinori, Yanai, Yoshiaki, Tsuzuki, Toyonori, Abe, Hideyuki, Arai, Kyoko, Yoshida, Ken-Ichiro, Kamai, Takao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2017
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790531/
https://ncbi.nlm.nih.gov/pubmed/29423114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23683
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