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Spontaneous Reconstitution of Functional Transmembrane Proteins During Bioorthogonal Phospholipid Membrane Synthesis

Transmembrane proteins are critical for signaling, transport, and metabolism, yet their reconstitution in synthetic membranes is often challenging. Non-enzymatic and chemoselective methods to generate phospholipid membranes in situ would be powerful tools for the incorporation of membrane proteins....

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Cole, Christian M., Brea, Roberto J., Kim, Young Hun, Hardy, Michael D., Yang, Jerry, Devaraj, Neal K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790194/
https://ncbi.nlm.nih.gov/pubmed/26316292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201504339
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