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miR-106b-5p promotes stem cell-like properties of hepatocellular carcinoma cells by targeting PTEN via PI3K/Akt pathway

BACKGROUND: The miRNA miR-106b-5p has been previously reported to be increased in hepatocellular carcinoma (HCC) tissues compared to cirrhotic tissues. The purpose of this study was to detect its expression in HCC cell lines with distinct metastatic potentials and to explore the molecular mechanisms...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Shi, Dong-Min, Bian, Xin-Yu, Qin, Cheng-Dong, Wu, Wei-Zhong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5790077/
https://ncbi.nlm.nih.gov/pubmed/29416358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S152611
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