Human Skeletal Muscle Possesses an Epigenetic Memory of Hypertrophy

It is unknown if adult human skeletal muscle has an epigenetic memory of earlier encounters with growth. We report, for the first time in humans, genome-wide DNA methylation (850,000 CpGs) and gene expression analysis after muscle hypertrophy (loading), return of muscle mass to baseline (unloading),...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Seaborne, Robert A., Strauss, Juliette, Cocks, Matthew, Shepherd, Sam, O’Brien, Thomas D., van Someren, Ken A., Bell, Phillip G., Murgatroyd, Christopher, Morton, James P., Stewart, Claire E., Sharples, Adam P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789890/
https://ncbi.nlm.nih.gov/pubmed/29382913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20287-3
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