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Structure of tick-borne encephalitis virus and its neutralization by a monoclonal antibody

Tick-borne encephalitis virus (TBEV) causes 13,000 cases of human meningitis and encephalitis annually. However, the structure of the TBEV virion and its interactions with antibodies are unknown. Here, we present cryo-EM structures of the native TBEV virion and its complex with Fab fragments of neut...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Füzik, Tibor, Formanová, Petra, Růžek, Daniel, Yoshii, Kentaro, Niedrig, Matthias, Plevka, Pavel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789857/
https://ncbi.nlm.nih.gov/pubmed/29382836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02882-0
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