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Mesenchymal stem cell-derived extracellular vesicles attenuate influenza virus-induced acute lung injury in a pig model

BACKGROUND: Mesenchymal stem (stromal) cells (MSCs) mediate their immunoregulatory and tissue repair functions by secreting paracrine factors, including extracellular vesicles (EVs). In several animal models of human diseases, MSC-EVs mimic the beneficial effects of MSCs. Influenza viruses cause ann...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Res Ther
Hauptverfasser: Khatri, Mahesh, Richardson, Levi Arthur, Meulia, Tea
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789598/
https://ncbi.nlm.nih.gov/pubmed/29378639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-018-0774-8
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