mTOR Cross-Talk in Cancer and Potential for Combination Therapy

The mammalian Target of Rapamycin (mTOR) pathway plays an essential role in sensing and integrating a variety of exogenous cues to regulate cellular growth and metabolism, in both physiological and pathological conditions. mTOR functions through two functionally and structurally distinct multi-compo...

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Detalles Bibliográficos
Publicado en:Cancers (Basel)
Autores principales: Conciatori, Fabiana, Ciuffreda, Ludovica, Bazzichetto, Chiara, Falcone, Italia, Pilotto, Sara, Bria, Emilio, Cognetti, Francesco, Milella, Michele
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789373/
https://ncbi.nlm.nih.gov/pubmed/29351204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10010023
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