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Targeting FLT3 Mutations in Acute Myeloid Leukemia
The FMS-like tyrosine kinase 3 (FLT3) pathway has an important role in cellular proliferation, survival, and differentiation. Acute myeloid leukemia (AML) patients with mutated FLT3 have a large disease burden at presentation and a dismal prognosis. A number of FLT3 inhibitors have been developed ov...
Guardat en:
| Publicat a: | Cells |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5789277/ https://ncbi.nlm.nih.gov/pubmed/29316714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells7010004 |
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