3′,4′-dihydroxyflavonol ameliorates endoplasmic reticulum stress-induced apoptosis and endothelial dysfunction in mice

Endoplasmic reticulum (ER) stress has been implicated in the development of hypertension 3 through the induction of endothelial impairment. As 3′,4′-dihydroxyflavonol (DiOHF) 4 reduces vascular injury caused by ischaemia/reperfusion or diabetes, and flavonols have been demonstrated to attenuate ER s...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Lau, Yeh Siang, Mustafa, Mohd Rais, Choy, Ker Woon, Chan, Stanley M. H., Potocnik, Simon, Herbert, Terence P., Woodman, Owen L.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5789000/
https://ncbi.nlm.nih.gov/pubmed/29379034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19584-8
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