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Reconstruction of cysteine biosynthesis using engineered cysteine-free enzymes

Amino acid biosynthesis pathways observed in nature typically require enzymes that are made with the amino acids they produce. For example, Escherichia coli produces cysteine from serine via two enzymes that contain cysteine: serine acetyltransferase (CysE) and O-acetylserine sulfhydrylase (CysK/Cys...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fujishima, Kosuke, Wang, Kendrick M., Palmer, Jesse A., Abe, Nozomi, Nakahigashi, Kenji, Endy, Drew, Rothschild, Lynn J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788988/
https://ncbi.nlm.nih.gov/pubmed/29379050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19920-y
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