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SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage

The cohesin complex is built upon the SMC1/SMC3 heterodimer, and mammalian meiocytes feature two variants of SMC1 named SMC1α and SMC1β. It is unclear why these two SMC1 variants have evolved. To determine unique versus redundant functions of SMC1β, we asked which of the known functions of SMC1β can...

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Bibliografische gegevens
Gepubliceerd in:Curr Biol
Hoofdauteurs: Biswas, Uddipta, Stevense, Michelle, Jessberger, Rolf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788747/
https://ncbi.nlm.nih.gov/pubmed/29337080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.12.020
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