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Keeping Pace with the Red Queen: Identifying the Genetic Basis of Susceptibility to Infectious Disease

Genome-wide association studies are widely used to identify “disease genes” conferring resistance/susceptibility to infectious diseases. Using a combination of mathematical models and simulations, we demonstrate that genetic interactions between hosts and parasites [genotype-by-genotype (G × G) inte...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: MacPherson, Ailene, Otto, Sarah P., Nuismer, Scott L.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5788537/
https://ncbi.nlm.nih.gov/pubmed/29223971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300481
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