Gravar-mail: Group-Based Optimization
of Potent and Cell-Active
Inhibitors of the von Hippel–Lindau (VHL) E3 Ubiquitin Ligase:
Structure–Activity Relationships Leading to the Chemical Probe
(2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
(VH298)