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Substrate Sorting by a Supercharged Nanoreactor
[Image: see text] Compartmentalization of proteases enables spatially and temporally controlled protein degradation in cells. Here we show that an engineered lumazine synthase protein cage, which possesses a negatively supercharged lumen, can exploit electrostatic effects to sort substrates for an e...
Shranjeno v:
| izdano v: | J Am Chem Soc |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical
Society
2017
|
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5788330/ https://ncbi.nlm.nih.gov/pubmed/29278496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b11210 |
| Oznake: |
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