Chitosan-DNA nanoparticles enhanced the immunogenicity of multivalent DNA vaccination on mice against Trueperella pyogenes infection

BACKGROUND: Trueperella pyogenes is a commensal and opportunistic pathogen that normally causes mastitis, liver abscesses and pneumonia of economically important livestock. To develop efficacious and potent vaccine against T. pyogenes, chimeric gene DNA vaccines were constructed and encapsulated in...

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Published in:J Nanobiotechnology
Main Authors: Huang, Ting, Song, Xuhao, Jing, Jie, Zhao, Kelei, Shen, Yongmei, Zhang, Xiuyue, Yue, Bisong
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787914/
https://ncbi.nlm.nih.gov/pubmed/29378591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-018-0337-2
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