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Rivaroxaban dose adjustment using thrombin generation in severe congenital protein C deficiency and warfarin-induced skin necrosis

Rivaroxaban was efficacious and safe in a child with protein C deficiency to prevent the recurrence of skin necrosis or venous thrombosis. The dosage of direct oral anticoagulants in children with thrombophilia is unclear; a thrombin generation assay may be useful to adjust it.

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Menon, Neethu, Sarode, Ravi, Zia, Ayesha
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787863/
https://ncbi.nlm.nih.gov/pubmed/29365322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017012047
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