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In‐solution antibody harvesting with a plant‐produced hydrophobin–Protein A fusion

Purification is a bottleneck and a major cost factor in the production of antibodies. We set out to engineer a bifunctional fusion protein from two building blocks, Protein A and a hydrophobin, aiming at low‐cost and scalable antibody capturing in solutions. Immunoglobulin‐binding Protein A is widel...

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Detalhes bibliográficos
Publicado no:Plant Biotechnol J
Main Authors: Kurppa, Katri, Reuter, Lauri J., Ritala, Anneli, Linder, Markus B., Joensuu, Jussi J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787837/
https://ncbi.nlm.nih.gov/pubmed/28640955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12780
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