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Structural basis for lipid binding and mechanism of the Mycobacterium tuberculosis Rv3802 phospholipase
The Mycobacterium tuberculosis rv3802c gene encodes an essential enzyme with thioesterase and phospholipase A activity. Overexpression of Rv3802 orthologs in Mycobacterium smegmatis and Corynebacterium glutamicum increases mycolate content and decreases glycerophospholipids. Although a role in modul...
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Publicado no: | J Biol Chem |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5787812/ https://ncbi.nlm.nih.gov/pubmed/29247008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000240 |
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