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Toll-Like Receptor 8 Agonist Strengthens the Protective Efficacy of ESAT-6 Immunization to Mycobacterium tuberculosis Infection

Accumulating evidence suggests important functions for human Toll-like receptor 8 in vivo in tuberculosis and autoimmune diseases. However, these studies are limited by the lack of specific agonists and by the fact that the homology of TLR8 in human and mice is not sufficient to rely on mouse models...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Tang, Jun, Sun, Mengmeng, Shi, Guiying, Xu, Yanfeng, Han, Yunlin, Li, Xiang, Dong, Wei, Zhan, Lingjun, Qin, Chuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787779/
https://ncbi.nlm.nih.gov/pubmed/29416532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01972
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