Dihydroartemisinin selectively inhibits PDGFRα-positive ovarian cancer growth and metastasis through inducing degradation of PDGFRα protein

To develop traditional medicines as modern pharmacotherapies, understanding their molecular mechanisms of action can be very helpful. We have recently reported that Artemisinin and its derivatives, which are clinically used anti-malarial drugs, have significant effects against ovarian cancer, but th...

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Detalhes bibliográficos
Publicado no:Cell Discov
Main Authors: Li, Xiaoguang, Ba, Qian, Liu, Yanling, Yue, Qingxi, Chen, Peizhan, Li, Jingquan, Zhang, Haibing, Ying, Hao, Ding, Qiurong, Song, Haiyun, Liu, Hong, Zhang, Ruiwen, Wang, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787695/
https://ncbi.nlm.nih.gov/pubmed/29387451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/celldisc.2017.42
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