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Gli is activated and promotes epithelial-mesenchymal transition in human esophageal adenocarcinoma

Esophageal adenocarcinoma (EAC) accounts for the most esophageal cancer cases in the US, and is notoriously aggressive. This study examines the role of Sonic Hedgehog (SHh)/Gli signaling in the regulation of epithelial-mesenchymal transition (EMT), a process tied to invasion and metastasis, in EAC....

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Wang, Lei, Jin, Joy Q., Zhou, Yong, Tian, Ziqiang, Jablons, David M., He, Biao
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787518/
https://ncbi.nlm.nih.gov/pubmed/29416661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22856
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