The inhibitory activity of gallic acid against DNA methylation: application of gallic acid on epigenetic therapy of human cancers

Epigenome aberrations have been observed in tobacco-associated human malignancies. (−)-epigallocatechin-3-gallate (EGCG) has been proven to modulate gene expression by targeting DNA methyltransferases (DNMTs) through a proposed mechanism involving the gallate moiety of EGCG. We show that gallic acid...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Weng, Yui-Ping, Hung, Pin-Feng, Ku, Wen-Yen, Chang, Chang-Yuan, Wu, Bo-Han, Wu, Ming-Han, Yao, Jau-Ying, Yang, Ji-Rui, Lee, Chia-Huei
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787471/
https://ncbi.nlm.nih.gov/pubmed/29416619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23015
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