What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis

Rapid and accurate drug susceptibility testing (DST) is essential for the treatment of multi- and extensively drug-resistant tuberculosis (M/XDR-TB). We compared the utility of genotypic DST assays with phenotypic DST (pDST) using Bactec 960 MGIT or Löwenstein-Jensen to construct M/XDR-TB treatment...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Heyckendorf, Jan, Andres, Sönke, Köser, Claudio U., Olaru, Ioana D., Schön, Thomas, Sturegård, Erik, Beckert, Patrick, Schleusener, Viola, Kohl, Thomas A., Hillemann, Doris, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J., Niemann, Stefan, Lange, Christoph, Merker, Matthias
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786814/
https://ncbi.nlm.nih.gov/pubmed/29133554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01550-17
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