What Is Resistance? Impact of Phenotypic versus Molecular Drug Resistance Testing on Therapy for Multi- and Extensively Drug-Resistant Tuberculosis

Rapid and accurate drug susceptibility testing (DST) is essential for the treatment of multi- and extensively drug-resistant tuberculosis (M/XDR-TB). We compared the utility of genotypic DST assays with phenotypic DST (pDST) using Bactec 960 MGIT or Löwenstein-Jensen to construct M/XDR-TB treatment...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Heyckendorf, Jan, Andres, Sönke, Köser, Claudio U., Olaru, Ioana D., Schön, Thomas, Sturegård, Erik, Beckert, Patrick, Schleusener, Viola, Kohl, Thomas A., Hillemann, Doris, Moradigaravand, Danesh, Parkhill, Julian, Peacock, Sharon J., Niemann, Stefan, Lange, Christoph, Merker, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786814/
https://ncbi.nlm.nih.gov/pubmed/29133554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01550-17
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