Fluconazole-Resistant Candida auris Is Susceptible to Salivary Histatin 5 Killing and to Intrinsic Host Defenses

Candida auris is a newly identified species causing invasive candidemia and candidiasis. It has broad multidrug resistance (MDR) not observed for other pathogenic Candida species. Histatin 5 (Hst 5) is a well-studied salivary cationic peptide with significant antifungal activity against Candida albi...

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Опубликовано в: :Antimicrob Agents Chemother
Главные авторы: Pathirana, Ruvini U., Friedman, Justin, Norris, Hannah L., Salvatori, Ornella, McCall, Andrew D., Kay, Jason, Edgerton, Mira
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2018
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Mechanisms of Action: Physiological Effects
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786754/
https://ncbi.nlm.nih.gov/pubmed/29158282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01872-17
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