A Spontaneous Mutation in Taar1 Impacts Methamphetamine-Related Traits Exclusively in DBA/2 Mice from a Single Vendor

Major gene effects on traits associated with substance use disorders are rare. Previous findings in methamphetamine drinking (MADR) lines of mice, bred for high or low voluntary MA intake, and in null mutants demonstrate a major impact of the trace amine-associated receptor 1 (Taar1) gene on a triad...

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Dades bibliogràfiques
Publicat a:Front Pharmacol
Autors principals: Reed, Cheryl, Baba, Harue, Zhu, Zhen, Erk, Jason, Mootz, John R., Varra, Nicholas M., Williams, Robert W., Phillips, Tamara J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2018
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786530/
https://ncbi.nlm.nih.gov/pubmed/29403379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00993
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