Effects of the antagomiRs 15b and 200b on the altered healing pattern of diabetic mice

BACKGROUND AND PURPOSE: Diabetic patients with non‐healing ulcers have a reduced expression of VEGF. Genetically diabetic mice have an altered expression pattern of VEGF and its receptor, VEGF receptor 2 (VEGFR‐2). In diabetic wounds, the microRNAs, miR15b and miR200b, which respectively inhibit VEG...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Pizzino, Gabriele, Irrera, Natasha, Galfo, Federica, Pallio, Giovanni, Mannino, Federica, D'amore, Angelica, Pellegrino, Enrica, Ieni, Antonio, Russo, Giuseppina T, Calapai, Marco, Altavilla, Domenica, Squadrito, Francesco, Bitto, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786458/
https://ncbi.nlm.nih.gov/pubmed/29178246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14113
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