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Disease-associated protein seeding suggests a dissociation between misfolded protein accumulation and neurodegeneration in prion disease
Chronic neurodegenerative diseases, such as prion diseases or Alzheimer's disease, are associated with progressive accumulation of host proteins which misfold and aggregate. Neurodegeneration is restricted to specific neuronal populations which show clear accumulation of misfolded proteins, whi...
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| 出版年: | Prion |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5786362/ https://ncbi.nlm.nih.gov/pubmed/29023184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336896.2017.1378289 |
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