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Cooperative interactions between VEGFR2 extracellular Ig-like subdomains ensure VEGFR2 dimerization

BACKGROUND: Prior studies have suggested that the interactions occurring between VEGFR2 extracellular domains in the absence of ligand are complex. Here we seek novel insights into these interactions, and into the role of the different Ig-like domains (D1 through D7) in VEGFR2 dimerization. METHODS:...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: King, Christopher, Wirth, Daniel, Workman, Samuel, Hristova, Kalina
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786268/
https://ncbi.nlm.nih.gov/pubmed/28847506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2017.08.021
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