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Induction of adipose and hepatic SWELL1 expression is required for maintaining systemic insulin-sensitivity in obesity

Obesity is associated with a loss of insulin-sensitivity and systemic dysglycemia, resulting in Type 2 diabetes, however the molecular mechanisms underlying this association are unclear. Through adipocyte patch-clamp studies, we recently showed that SWELL1 is required for the Volume-Regulated Anion...

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Detalhes bibliográficos
Publicado no:Channels (Austin)
Main Authors: Xie, Litao, Zhang, Yanhui, Gunasekar, Susheel K., Mishra, Anil, Cao, Lei, Sah, Rajan
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786185/
https://ncbi.nlm.nih.gov/pubmed/28873008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336950.2017.1373225
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