Novel mechanisms of Collagenase Santyl Ointment (CSO) in wound macrophage polarization and resolution of wound inflammation

Collagenases are useful in enzymatic wound debridement. Clostridial collagenase, marketed as Collagenase Santyl Ointment (CSO), is FDA approved for such use. Building on the scientific premise that collagenases as well as collagen degradation products may regulate immune cell function, we sought to...

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Опубликовано в: :Sci Rep
Главные авторы: Das, Amitava, Datta, Soma, Roche, Eric, Chaffee, Scott, Jose, Elizabeth, Shi, Lei, Grover, Komel, Khanna, Savita, Sen, Chandan K., Roy, Sashwati
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786052/
https://ncbi.nlm.nih.gov/pubmed/29374192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-19879-w
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