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An xQTL map integrates the genetic architecture of the human brain’s transcriptome and epigenome
We report a novel multi-omic resource generated by applying quantitative trait locus (xQTL) analyses to RNA sequence, DNA methylation, and histone acetylation data from the dorsolateral prefrontal cortex of 411 older adult individuals that have all three data types. We identify SNPs significantly as...
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Publicado no: | Nat Neurosci |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5785926/ https://ncbi.nlm.nih.gov/pubmed/28869584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.4632 |
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