Leptin-induced ER-α-positive breast cancer cell viability and migration is mediated by suppressing CCN5-signaling via activating JAK/AKT/STAT-pathway

BACKGROUND: In menopausal women, one of the critical risk factors for breast cancer is obesity/adiposity. It is evident from various studies that leptin, a 16 kDa protein hormone overproduced in obese people, plays the critical role in neovascularization and tumorigenesis in breast and other organs....

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Haque, Inamul, Ghosh, Arnab, Acup, Seth, Banerjee, Snigdha, Dhar, Kakali, Ray, Amitabha, Sarkar, Sandipto, Kambhampati, Suman, Banerjee, Sushanta K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785848/
https://ncbi.nlm.nih.gov/pubmed/29370782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-3993-6
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