Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons

Parkinson’s disease is characterized by the loss of dopamine (DA) neurons in the substantia nigra pars compacta (SNc). DA neurons in the ventral tegmental area are more resistant to this degeneration than those in the SNc, though the mechanisms for selective resistance or vulnerability remain poorly...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Steinkellner, Thomas, Zell, Vivien, Farino, Zachary J., Sonders, Mark S., Villeneuve, Michael, Freyberg, Robin J., Przedborski, Serge, Lu, Wei, Freyberg, Zachary, Hnasko, Thomas S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5785252/
https://ncbi.nlm.nih.gov/pubmed/29337309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI95795
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