Ethyl pyruvate inhibits oxidation of LDL in vitro and attenuates oxLDL toxicity in EA.hy926 cells

BACKGROUND: Ethyl pyruvate (EP) exerts anti-inflammatory and anti-oxidative properties. The aim of our study was to investigate whether EP is capable of inhibiting the oxidation of LDL, a crucial step in atherogenesis. Additionally, we examined whether EP attenuates the cytotoxic effects of highly o...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rossmann, Christine, Nusshold, Christoph, Paar, Margret, Ledinski, Gerhard, Tafeit, Erwin, Koestenberger, Martin, Bernhart, Eva Maria, Sattler, Wolfgang, Cvirn, Gerhard, Hallström, Seth
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784938/
https://ncbi.nlm.nih.gov/pubmed/29370236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191477
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