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Inferring hidden causal relations between pathway members using reduced Google matrix of directed biological networks

Signaling pathways represent parts of the global biological molecular network which connects them into a seamless whole through complex direct and indirect (hidden) crosstalk whose structure can change during development or in pathological conditions. We suggest a novel methodology, called Googlomic...

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Udgivet i:PLoS One
Main Authors: Lages, José, Shepelyansky, Dima L., Zinovyev, Andrei
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5784915/
https://ncbi.nlm.nih.gov/pubmed/29370181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190812
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